Response to „No evidence of SARS-CoV-2 infection by PCR or serology in children with pseudochilblain”
We read with interest the article by Caselli D et al., reporting a case series of 38 children with chilblain-like lesions (CLL). Testing for SARS-CoV-2 , including PCR, rapid test serology and ELISA method for IgA and IgG antibodies yielded negative results in all cases. They concluded that their data do not allow them to support the relationship of CLL with SARS-CoV-2 infection. So far, data in the literature studying CLL documented a very low percentage of laboratory confirmed SARS-CoV-2. However, Colmenero and colleagues were able to detect SARS-CoV-2 in endothelial cells of cutaneous chilblain lesions by immunohistochemistry methods in 7 pediatric patients with negative nasopharyngeal swabs.
Orphan GPCR SP9155 agonist P550 (mouse, rat)
T40685-1g
TargetMol Chemicals
1g
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat)
Orphan GPCR SP9155 agonist P550 (mouse, rat)
T40685-1mg
TargetMol Chemicals
1mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat)
Orphan GPCR SP9155 agonist P550 (mouse, rat)
T40685-50mg
TargetMol Chemicals
50mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat)
Orphan GPCR SP9155 agonist P550 (mouse, rat)
T40685-5mg
TargetMol Chemicals
5mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat)
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
MBS5785731-10mg
MyBiosource
10(mg
EUR 645
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
MBS5785731-1mg
MyBiosource
1(mg
EUR 250
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
MBS5785731-5mg
MyBiosource
5(mg
EUR 455
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
T40685L-10mg
TargetMol Chemicals
10mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
T40685L-1g
TargetMol Chemicals
1g
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
T40685L-1mg
TargetMol Chemicals
1mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
T40685L-50mg
TargetMol Chemicals
50mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
T40685L-5mg
TargetMol Chemicals
5mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Phosphatase Orphan-2 (Recombinant)
20-abx073747
Abbexa
Ask for price
Ask for price
Ask for price
Phosphatase Orphan-1 (Recombinant)
20-abx073910
Abbexa
Ask for price
Ask for price
Ask for price
TR3 Orphan Receptor Antibody
GWB-Q00589
GenWay Biotech
0.1 mg
Ask for price
Recombinant Human Phosphatase Orphan-2
MBS145413-0002mg
MyBiosource
0.002mg
EUR 240
Recombinant Human Phosphatase Orphan-2
MBS145413-001mg
MyBiosource
0.01mg
EUR 310
Recombinant Human Phosphatase Orphan-2
MBS145413-1mg
MyBiosource
1mg
EUR 5345
Recombinant Human Phosphatase Orphan-2
MBS145413-5x1mg
MyBiosource
5x1mg
EUR 23725
Recombinant Human Phosphatase Orphan-1
MBS143372-0002mg
MyBiosource
0.002mg
EUR 240
Recombinant Human Phosphatase Orphan-1
MBS143372-001mg
MyBiosource
0.01mg
EUR 310
Recombinant Human Phosphatase Orphan-1
MBS143372-1mg
MyBiosource
1mg
EUR 6145
Recombinant Human Phosphatase Orphan-1
MBS143372-5x1mg
MyBiosource
5x1mg
EUR 27325
Phosphatase Orphan-2 Human Recombinant
rAP-1526
Angio Proteomie
Inquiry
Ask for price
Phosphatase Orphan-1 Human Recombinant
rAP-1537
Angio Proteomie
Inquiry
Ask for price
Orphan Receptor Peptide Ligand Library
L-005
PHOENIX PEPTIDE
150 peptides
EUR 7938
GOAT ANTI HUMAN TR3 ORPHAN RECEPTOR
MBS224277-01mg
MyBiosource
0.1mg
EUR 635
GOAT ANTI HUMAN TR3 ORPHAN RECEPTOR
MBS224277-5x01mg
MyBiosource
5x0.1mg
EUR 2695
Recombinant Tetraspanning orphan receptor (TOR)
MBS7032068-002mg
MyBiosource
0.02mg
EUR 1590
Recombinant Tetraspanning orphan receptor (TOR)
MBS7032068-01mg
MyBiosource
0.1mg
EUR 2550
Recombinant Tetraspanning orphan receptor (TOR)
MBS7032068-5x01mg
MyBiosource
5x0.1mg
EUR 11430
Anti- Orphan nuclear receptor NR1D1 Antibody
GWB-8CE768
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR1D1 Antibody
GWB-90CFB3
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR6A1 Antibody
GWB-F872CA
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR6A1 Antibody
GWB-523200
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR1D2 Antibody
GWB-692AC1
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR1D1 Antibody
GWB-797370
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR6A1 Antibody
GWB-7EBAAA
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR5A2 Antibody
GWB-83F95E
GenWay Biotech
0.05 ml
Ask for price
Mouse Anti Respiratory Enteric Orphan Virus
MBS140339-05mg
MyBiosource
0.5mg
EUR 440
Mouse Anti Respiratory Enteric Orphan Virus
MBS140339-1mg
MyBiosource
1mg
EUR 600
Mouse Anti Respiratory Enteric Orphan Virus
MBS140339-5x1mg
MyBiosource
5x1mg
EUR 2375
Anti- Orphan nuclear receptor EAR-2 Antibody
GWB-8AE8C4
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor EAR-2 Antibody
GWB-B9F321
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor EAR-2 Antibody
GWB-D37B4B
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor EAR-2 Antibody
GWB-835BD4
GenWay Biotech
0.05 ml
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx027769-400l
Abbexa
400 µl
EUR 518.75
RAR Related Orphan Receptor Beta (RORB) Antibody
abx027769-400ul
Abbexa
400 ul
EUR 627.6
RAR Related Orphan Receptor Beta (RORB) Antibody
abx027769-80l
Abbexa
80 µl
EUR 250
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214131-100l
Abbexa
100 µl
EUR 350
RAR Related Orphan Receptor Beta (RORB) Antibody
20-abx214131
Abbexa
Ask for price
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214131-200l
Abbexa
200 µl
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214131-40l
Abbexa
40 µl
EUR 250
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214132-100l
Abbexa
100 µl
EUR 350
RAR Related Orphan Receptor Beta (RORB) Antibody
20-abx214132
Abbexa
Ask for price
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214132-200l
Abbexa
200 µl
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214132-40l
Abbexa
40 µl
EUR 250
Rar-Related Orphan Receptor A (RORA) Antibody
abx115045-100l
Abbexa
100 µl
EUR 612.5
Rar-Related Orphan Receptor A (RORA) Antibody
20-abx115045
Abbexa
Ask for price
Ask for price
Rar-Related Orphan Receptor B (RORB) Antibody
abx115046-100l
Abbexa
100 µl
EUR 612.5
Rar-Related Orphan Receptor B (RORB) Antibody
20-abx115046
Abbexa
Ask for price
Ask for price
Rar-Related Orphan Receptor C (RORC) Antibody
abx115047-100l
Abbexa
100 µl
EUR 612.5
Rar-Related Orphan Receptor C (RORC) Antibody
20-abx115047
Abbexa
Ask for price
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx237388-100g
Abbexa
100 µg
EUR 350
RAR Related Orphan Receptor Beta (RORB) Antibody
abx237388-100ug
Abbexa
100 ug
EUR 610.8
RAR Related Orphan Receptor Gamma (RORG) Protein
20-abx261968
Abbexa
Ask for price
Ask for price
Ask for price
Anti- RAR-related orphan receptor B Antibody
GWB-DA40DA
GenWay Biotech
0.05 ml
Ask for price
Anti- RAR-related orphan receptor B Antibody
GWB-B1C150
GenWay Biotech
0.05 ml
Ask for price
Anti- RAR-related orphan receptor B Antibody
GWB-B781E5
GenWay Biotech
0.05 ml
Ask for price
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx025951-400l
Abbexa
400 µl
EUR 518.75
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx025951-400ul
Abbexa
400 ul
EUR 627.6
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx025951-80l
Abbexa
80 µl
EUR 281.25
RAR Related Orphan Receptor Gamma (RORG) Antibody
abx013514-100g
Abbexa
100 µg
EUR 237.5
RAR Related Orphan Receptor Gamma (RORG) Antibody
20-abx013514
Abbexa
Ask for price
Ask for price
Ask for price
Ask for price
10 ug
100 ug
200 ug
300 µg
RAR Related Orphan Receptor Gamma (RORG) Antibody
abx013514-10g
Abbexa
10 µg
EUR 43.75
RAR Related Orphan Receptor Gamma (RORG) Antibody
abx013514-200g
Abbexa
200 µg
EUR 312.5
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx005288-100l
Abbexa
100 µl
EUR 400
RAR Related Orphan Receptor Alpha (RORA) Antibody
20-abx005288
Abbexa
Ask for price
Ask for price
Ask for price
Ask for price
20 ul
50 ul
100 ul
200 ul
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx005288-20l
Abbexa
20 µl
EUR 175
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx005288-50l
Abbexa
50 µl
EUR 275
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
abx130085-100l
Abbexa
100 µl
EUR 287.5
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
20-abx130085
Abbexa
Ask for price
Ask for price
Ask for price
Ask for price
Ask for price
10 ug
50 ug
100 ug
200 ug
1 mg
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
abx130085-1ml
Abbexa
1 ml
EUR 812.5
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
abx130085-200l
Abbexa
200 µl
EUR 362.5
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
20-abx173779
Abbexa
Ask for price
Ask for price
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
abx173779-1ml
Abbexa
1 ml
EUR 850
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx338779-100g
Abbexa
100 µg
EUR 362.5
RAR Related Orphan Receptor Alpha (RORA) Antibody
20-abx338779
Abbexa
Ask for price
Ask for price
Ask for price
Ask for price
Ask for price
20 ug
50 ug
100 ug
200 ug
1 mg
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx338779-20g
Abbexa
20 µg
EUR 162.5
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx338779-50g
Abbexa
50 µg
EUR 250
RAR Related Orphan Receptor Gamma (RORg) Antibody
20-abx178212
Abbexa
Ask for price
Ask for price
RAR Related Orphan Receptor Gamma (RORg) Antibody
abx178212-96tests
Abbexa
96 tests
EUR 287.5
RAR Related Orphan Receptor Gamma (RORG) Antibody
abx217274-100tests
Abbexa
100 tests
Ask for price
RAR Related Orphan Receptor Gamma (RORG) Antibody
abx217274-200tests
Abbexa
200 tests
Ask for price
RAR Related Orphan Receptor Gamma (RORG) Antibody
abx217274-20tests
Abbexa
20 tests
EUR 350
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx211380-100l
Abbexa
100 µl
EUR 350
RAR Related Orphan Receptor Alpha (RORA) Antibody
20-abx211380
Abbexa
Ask for price
Ask for price
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx211380-50l
Abbexa
50 µl
EUR 250
Complement C4 Gene Copy Number Variation Genotyping by High Resolution Melting PCR
Background: Complement C4 gene copy number variation plays an important role as a determinant of genetic susceptibility to common diseases, such as systemic lupus erythematosus, schizophrenia, rheumatoid arthritis, and infectious diseases. This study aimed to develop an assay for the quantification of copy number variations in the C4 locus.
Methods: the assay was based on a gene ratio analysis copy enumeration (GRACE) PCR combined with high resolution melting (HRM) PCR . The test was optimized using samples of a known genotype and validated with 72 DNA samples from healthy blood donors.
Results: to validate the assay, standard curves were generated by plotting the C4/RP1 ratio values against copy number variation (CNV) for each gene, using genomic DNA with known C4 CNV. The range of copy numbers in control individuals was comparable to distributions observed in previous studies of European descent.
Conclusions: the method herein described significantly simplifies C4 CNV diagnosis to validate the assay.
Detection of BRAF V600E Mutation in Ganglioglioma and Pilocytic Astrocytoma by Immunohistochemistry and Real-Time PCR -Based Idylla Test
The BRAF V600E mutation is an important oncological target in certain central nervous system (CNS) tumors, for which a possible application of BRAF-targeted therapy grows continuously. In the present study, we aim to determine the prevalence of BRAF V600E mutations in a series of ganglioglioma (GG) and pilocytic astrocytoma (PA) cases. Simultaneously, we decided to verify whether the combination of fully automated tests-BRAF-VE1 immunohistochemistry (IHC) and Idylla BRAF mutation assay-may be useful to accurately predict it in the case of specified CNS tumors.
The study included 49 formalin-fixed, paraffin-embedded tissues, of which 15 were GG and 34 PA. Immunohistochemistry with anti-BRAF V600E (VE1) antibody was performed on tissue sections using the VentanaBenchMark ULTRA platform. All positive or equivocal cases on IHC and selected negative ones were further assessed using the Idylla BRAF mutation assay coupled with the Idylla platform. The BRAF-VE1 IHC was positive in 6 (6/49; 12.3%) and negative in 39 samples (39/49; 79.6%). The interpretation of immunostaining results was complicated in 4 cases, of which 1 tested positive for the Idylla BRAF mutation assay. Therefore, the overall positivity rate was 14.3%. This included 2 cases of GG and 5 cases of PA. Our study found that BRAF V600E mutations are moderately frequent in PA and GG and that for these tumor entities, IHC VE1 is suitable for screening purposes, but all negative, equivocal, and weak positive cases should be further tested with molecular biology techniques, of which the Idylla system seems to be a promising tool.
Establishment of an SYBR Green-based real-time PCR assay for porcine circovirus type 4 detection
Porcine circovirus 4 (PCV4) is a novel circovirus first discovered in China in April 2019. Here, we established an SYBR Green I-based real-time PCR for quantitative detection of PCV4. A pair of specific primers was designed based on the conserved region of Cap of PCV4. The standard curve of the established real-time PCR assay showed a good linear relationship.
The sensitivity of the established real-time PCR was 100 times greater than that of conventional PCR, and the detection limit of the assay was 3 × 101 copies. There was no cross-reactivity with other swine DNA viruses, showing good specificity. The intra-group variation coefficient was 0.37-0.78%, and the inter-group variation coefficient was 0.57-0.94%, indicating that the assay has good repeatability. Moreover, the analysis of clinical samples showed that the positive detection rate of PCV4 was 10.71% (18/168), while that of conventional PCR was 8.93% (15/168). Interestingly, co-infection with PCV2 or PCV3, or both PCV2 and PCV3 , was also detected. In conclusion, the established SYBR Green I-based real-time PCR may be a cost-effective and rapid method for PCV4 clinical diagnosis.
Orphan GPCR SP9155 agonist P550 (mouse, rat)
T40685-50mg
TargetMol Chemicals
50mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat)
Orphan GPCR SP9155 agonist P550 (mouse, rat)
T40685-5mg
TargetMol Chemicals
5mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat)
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
MBS5785731-10mg
MyBiosource
10(mg
EUR 645
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
MBS5785731-1mg
MyBiosource
1(mg
EUR 250
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
MBS5785731-5mg
MyBiosource
5(mg
EUR 455
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
T40685L-10mg
TargetMol Chemicals
10mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
T40685L-1g
TargetMol Chemicals
1g
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
T40685L-1mg
TargetMol Chemicals
1mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
T40685L-50mg
TargetMol Chemicals
50mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
T40685L-5mg
TargetMol Chemicals
5mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Phosphatase Orphan-2 (Recombinant)
20-abx073747
Abbexa
Ask for price
Ask for price
Ask for price
Phosphatase Orphan-1 (Recombinant)
20-abx073910
Abbexa
Ask for price
Ask for price
Ask for price
TR3 Orphan Receptor Antibody
GWB-Q00589
GenWay Biotech
0.1 mg
Ask for price
Recombinant Human Phosphatase Orphan-2
MBS145413-0002mg
MyBiosource
0.002mg
EUR 240
Recombinant Human Phosphatase Orphan-2
MBS145413-001mg
MyBiosource
0.01mg
EUR 310
Recombinant Human Phosphatase Orphan-2
MBS145413-1mg
MyBiosource
1mg
EUR 5345
Recombinant Human Phosphatase Orphan-2
MBS145413-5x1mg
MyBiosource
5x1mg
EUR 23725
Recombinant Human Phosphatase Orphan-1
MBS143372-0002mg
MyBiosource
0.002mg
EUR 240
Recombinant Human Phosphatase Orphan-1
MBS143372-001mg
MyBiosource
0.01mg
EUR 310
Recombinant Human Phosphatase Orphan-1
MBS143372-1mg
MyBiosource
1mg
EUR 6145
Recombinant Human Phosphatase Orphan-1
MBS143372-5x1mg
MyBiosource
5x1mg
EUR 27325
Phosphatase Orphan-2 Human Recombinant
rAP-1526
Angio Proteomie
Inquiry
Ask for price
Phosphatase Orphan-1 Human Recombinant
rAP-1537
Angio Proteomie
Inquiry
Ask for price
Orphan Receptor Peptide Ligand Library
L-005
PHOENIX PEPTIDE
150 peptides
EUR 7938
GOAT ANTI HUMAN TR3 ORPHAN RECEPTOR
MBS224277-01mg
MyBiosource
0.1mg
EUR 635
GOAT ANTI HUMAN TR3 ORPHAN RECEPTOR
MBS224277-5x01mg
MyBiosource
5x0.1mg
EUR 2695
Recombinant Tetraspanning orphan receptor (TOR)
MBS7032068-002mg
MyBiosource
0.02mg
EUR 1590
Recombinant Tetraspanning orphan receptor (TOR)
MBS7032068-01mg
MyBiosource
0.1mg
EUR 2550
Recombinant Tetraspanning orphan receptor (TOR)
MBS7032068-5x01mg
MyBiosource
5x0.1mg
EUR 11430
Anti- Orphan nuclear receptor NR1D1 Antibody
GWB-8CE768
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR1D1 Antibody
GWB-90CFB3
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR6A1 Antibody
GWB-F872CA
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR6A1 Antibody
GWB-523200
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR1D2 Antibody
GWB-692AC1
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR1D1 Antibody
GWB-797370
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR6A1 Antibody
GWB-7EBAAA
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR5A2 Antibody
GWB-83F95E
GenWay Biotech
0.05 ml
Ask for price
Mouse Anti Respiratory Enteric Orphan Virus
MBS140339-05mg
MyBiosource
0.5mg
EUR 440
Mouse Anti Respiratory Enteric Orphan Virus
MBS140339-1mg
MyBiosource
1mg
EUR 600
Mouse Anti Respiratory Enteric Orphan Virus
MBS140339-5x1mg
MyBiosource
5x1mg
EUR 2375
Anti- Orphan nuclear receptor EAR-2 Antibody
GWB-8AE8C4
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor EAR-2 Antibody
GWB-B9F321
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor EAR-2 Antibody
GWB-D37B4B
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor EAR-2 Antibody
GWB-835BD4
GenWay Biotech
0.05 ml
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx027769-400l
Abbexa
400 µl
EUR 518.75
RAR Related Orphan Receptor Beta (RORB) Antibody
abx027769-400ul
Abbexa
400 ul
EUR 627.6
RAR Related Orphan Receptor Beta (RORB) Antibody
abx027769-80l
Abbexa
80 µl
EUR 250
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214131-100l
Abbexa
100 µl
EUR 350
RAR Related Orphan Receptor Beta (RORB) Antibody
20-abx214131
Abbexa
Ask for price
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214131-200l
Abbexa
200 µl
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214131-40l
Abbexa
40 µl
EUR 250
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214132-100l
Abbexa
100 µl
EUR 350
RAR Related Orphan Receptor Beta (RORB) Antibody
20-abx214132
Abbexa
Ask for price
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214132-200l
Abbexa
200 µl
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214132-40l
Abbexa
40 µl
EUR 250
Rar-Related Orphan Receptor A (RORA) Antibody
abx115045-100l
Abbexa
100 µl
EUR 612.5
Rar-Related Orphan Receptor A (RORA) Antibody
20-abx115045
Abbexa
Ask for price
Ask for price
Rar-Related Orphan Receptor B (RORB) Antibody
abx115046-100l
Abbexa
100 µl
EUR 612.5
Rar-Related Orphan Receptor B (RORB) Antibody
20-abx115046
Abbexa
Ask for price
Ask for price
Rar-Related Orphan Receptor C (RORC) Antibody
abx115047-100l
Abbexa
100 µl
EUR 612.5
Rar-Related Orphan Receptor C (RORC) Antibody
20-abx115047
Abbexa
Ask for price
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx237388-100g
Abbexa
100 µg
EUR 350
RAR Related Orphan Receptor Beta (RORB) Antibody
abx237388-100ug
Abbexa
100 ug
EUR 610.8
RAR Related Orphan Receptor Gamma (RORG) Protein
20-abx261968
Abbexa
Ask for price
Ask for price
Ask for price
Anti- RAR-related orphan receptor B Antibody
GWB-DA40DA
GenWay Biotech
0.05 ml
Ask for price
Anti- RAR-related orphan receptor B Antibody
GWB-B1C150
GenWay Biotech
0.05 ml
Ask for price
Anti- RAR-related orphan receptor B Antibody
GWB-B781E5
GenWay Biotech
0.05 ml
Ask for price
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx025951-400l
Abbexa
400 µl
EUR 518.75
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx025951-400ul
Abbexa
400 ul
EUR 627.6
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx025951-80l
Abbexa
80 µl
EUR 281.25
RAR Related Orphan Receptor Gamma (RORG) Antibody
abx013514-100g
Abbexa
100 µg
EUR 237.5
RAR Related Orphan Receptor Gamma (RORG) Antibody
20-abx013514
Abbexa
Ask for price
Ask for price
Ask for price
Ask for price
10 ug
100 ug
200 ug
300 µg
RAR Related Orphan Receptor Gamma (RORG) Antibody
abx013514-10g
Abbexa
10 µg
EUR 43.75
RAR Related Orphan Receptor Gamma (RORG) Antibody
abx013514-200g
Abbexa
200 µg
EUR 312.5
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx005288-100l
Abbexa
100 µl
EUR 400
RAR Related Orphan Receptor Alpha (RORA) Antibody
20-abx005288
Abbexa
Ask for price
Ask for price
Ask for price
Ask for price
20 ul
50 ul
100 ul
200 ul
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx005288-20l
Abbexa
20 µl
EUR 175
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx005288-50l
Abbexa
50 µl
EUR 275
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
abx130085-100l
Abbexa
100 µl
EUR 287.5
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
20-abx130085
Abbexa
Ask for price
Ask for price
Ask for price
Ask for price
Ask for price
10 ug
50 ug
100 ug
200 ug
1 mg
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
abx130085-1ml
Abbexa
1 ml
EUR 812.5
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
abx130085-200l
Abbexa
200 µl
EUR 362.5
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
20-abx173779
Abbexa
Ask for price
Ask for price
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
abx173779-1ml
Abbexa
1 ml
EUR 850
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx338779-100g
Abbexa
100 µg
EUR 362.5
RAR Related Orphan Receptor Alpha (RORA) Antibody
20-abx338779
Abbexa
Ask for price
Ask for price
Ask for price
Ask for price
Ask for price
20 ug
50 ug
100 ug
200 ug
1 mg
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx338779-20g
Abbexa
20 µg
EUR 162.5
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx338779-50g
Abbexa
50 µg
EUR 250
RAR Related Orphan Receptor Gamma (RORg) Antibody
20-abx178212
Abbexa
Ask for price
Ask for price
RAR Related Orphan Receptor Gamma (RORg) Antibody
abx178212-96tests
Abbexa
96 tests
EUR 287.5
RAR Related Orphan Receptor Gamma (RORG) Antibody
abx217274-100tests
Abbexa
100 tests
Ask for price
RAR Related Orphan Receptor Gamma (RORG) Antibody
abx217274-200tests
Abbexa
200 tests
Ask for price
Complement C4 Gene Copy Number Variation Genotyping by High Resolution Melting PCR
Background: Complement C4 gene copy number variation plays an important role as a determinant of genetic susceptibility to common diseases, such as systemic lupus erythematosus, schizophrenia, rheumatoid arthritis, and infectious diseases. This study aimed to develop an assay for the quantification of copy number variations in the C4 locus.
Methods: the assay was based on a gene ratio analysis copy enumeration (GRACE) PCR combined with high resolution melting (HRM) PCR . The test was optimized using samples of a known genotype and validated with 72 DNA samples from healthy blood donors.
Results: to validate the assay, standard curves were generated by plotting the C4/RP1 ratio values against copy number variation (CNV) for each gene, using genomic DNA with known C4 CNV. The range of copy numbers in control individuals was comparable to distributions observed in previous studies of European descent.
Conclusions: the method herein described significantly simplifies C4 CNV diagnosis to validate the assay.
Detection of BRAF V600E Mutation in Ganglioglioma and Pilocytic Astrocytoma by Immunohistochemistry and Real-Time PCR -Based Idylla Test
The BRAF V600E mutation is an important oncological target in certain central nervous system (CNS) tumors, for which a possible application of BRAF-targeted therapy grows continuously. In the present study, we aim to determine the prevalence of BRAF V600E mutations in a series of ganglioglioma (GG) and pilocytic astrocytoma (PA) cases. Simultaneously, we decided to verify whether the combination of fully automated tests-BRAF-VE1 immunohistochemistry (IHC) and Idylla BRAF mutation assay-may be useful to accurately predict it in the case of specified CNS tumors.
The study included 49 formalin-fixed, paraffin-embedded tissues, of which 15 were GG and 34 PA. Immunohistochemistry with anti-BRAF V600E (VE1) antibody was performed on tissue sections using the VentanaBenchMark ULTRA platform. All positive or equivocal cases on IHC and selected negative ones were further assessed using the Idylla BRAF mutation assay coupled with the Idylla platform. The BRAF-VE1 IHC was positive in 6 (6/49; 12.3%) and negative in 39 samples (39/49; 79.6%). The interpretation of immunostaining results was complicated in 4 cases, of which 1 tested positive for the Idylla BRAF mutation assay. Therefore, the overall positivity rate was 14.3%. This included 2 cases of GG and 5 cases of PA. Our study found that BRAF V600E mutations are moderately frequent in PA and GG and that for these tumor entities, IHC VE1 is suitable for screening purposes, but all negative, equivocal, and weak positive cases should be further tested with molecular biology techniques, of which the Idylla system seems to be a promising tool.
Establishment of an SYBR Green-based real-time PCR assay for porcine circovirus type 4 detection
Porcine circovirus 4 (PCV4) is a novel circovirus first discovered in China in April 2019. Here, we established an SYBR Green I-based real-time PCR for quantitative detection of PCV4. A pair of specific primers was designed based on the conserved region of Cap of PCV4. The standard curve of the established real-time PCR assay showed a good linear relationship. The sensitivity of the established real-time PCR was 100 times greater than that of conventional PCR, and the detection limit of the assay was 3 × 101 copies. There was no cross-reactivity with other swine DNA viruses, showing good specificity. The intra-group variation coefficient was 0.37-0.78%, and the inter-group variation coefficient was 0.57-0.94%, indicating that the assay has good repeatability. Moreover, the analysis of clinical samples showed that the positive detection rate of PCV4 was 10.71% (18/168), while that of conventional PCR was 8.93% (15/168). Interestingly, co-infection with PCV2 or PCV3, or both PCV2 and PCV3 , was also detected. In conclusion, the established SYBR Green I-based real-time PCR may be a cost-effective and rapid method for PCV4 clinical diagnosis.
Orphan GPCR SP9155 agonist P550 (mouse, rat)
T40685-50mg
TargetMol Chemicals
50mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat)
Orphan GPCR SP9155 agonist P550 (mouse, rat)
T40685-5mg
TargetMol Chemicals
5mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat)
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
MBS5785731-10mg
MyBiosource
10(mg
EUR 645
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
MBS5785731-1mg
MyBiosource
1(mg
EUR 250
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
MBS5785731-5mg
MyBiosource
5(mg
EUR 455
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
T40685L-10mg
TargetMol Chemicals
10mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
T40685L-1g
TargetMol Chemicals
1g
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
T40685L-1mg
TargetMol Chemicals
1mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
T40685L-50mg
TargetMol Chemicals
50mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
T40685L-5mg
TargetMol Chemicals
5mg
Ask for price
Description: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Phosphatase Orphan-2 (Recombinant)
20-abx073747
Abbexa
Ask for price
Ask for price
Ask for price
Phosphatase Orphan-1 (Recombinant)
20-abx073910
Abbexa
Ask for price
Ask for price
Ask for price
TR3 Orphan Receptor Antibody
GWB-Q00589
GenWay Biotech
0.1 mg
Ask for price
Recombinant Human Phosphatase Orphan-2
MBS145413-0002mg
MyBiosource
0.002mg
EUR 240
Recombinant Human Phosphatase Orphan-2
MBS145413-001mg
MyBiosource
0.01mg
EUR 310
Recombinant Human Phosphatase Orphan-2
MBS145413-1mg
MyBiosource
1mg
EUR 5345
Recombinant Human Phosphatase Orphan-2
MBS145413-5x1mg
MyBiosource
5x1mg
EUR 23725
Recombinant Human Phosphatase Orphan-1
MBS143372-0002mg
MyBiosource
0.002mg
EUR 240
Recombinant Human Phosphatase Orphan-1
MBS143372-001mg
MyBiosource
0.01mg
EUR 310
Recombinant Human Phosphatase Orphan-1
MBS143372-1mg
MyBiosource
1mg
EUR 6145
Recombinant Human Phosphatase Orphan-1
MBS143372-5x1mg
MyBiosource
5x1mg
EUR 27325
Phosphatase Orphan-2 Human Recombinant
rAP-1526
Angio Proteomie
Inquiry
Ask for price
Phosphatase Orphan-1 Human Recombinant
rAP-1537
Angio Proteomie
Inquiry
Ask for price
Orphan Receptor Peptide Ligand Library
L-005
PHOENIX PEPTIDE
150 peptides
EUR 7938
GOAT ANTI HUMAN TR3 ORPHAN RECEPTOR
MBS224277-01mg
MyBiosource
0.1mg
EUR 635
GOAT ANTI HUMAN TR3 ORPHAN RECEPTOR
MBS224277-5x01mg
MyBiosource
5x0.1mg
EUR 2695
Recombinant Tetraspanning orphan receptor (TOR)
MBS7032068-002mg
MyBiosource
0.02mg
EUR 1590
Recombinant Tetraspanning orphan receptor (TOR)
MBS7032068-01mg
MyBiosource
0.1mg
EUR 2550
Recombinant Tetraspanning orphan receptor (TOR)
MBS7032068-5x01mg
MyBiosource
5x0.1mg
EUR 11430
Anti- Orphan nuclear receptor NR1D1 Antibody
GWB-8CE768
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR1D1 Antibody
GWB-90CFB3
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR6A1 Antibody
GWB-F872CA
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR6A1 Antibody
GWB-523200
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR1D2 Antibody
GWB-692AC1
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR1D1 Antibody
GWB-797370
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR6A1 Antibody
GWB-7EBAAA
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor NR5A2 Antibody
GWB-83F95E
GenWay Biotech
0.05 ml
Ask for price
Mouse Anti Respiratory Enteric Orphan Virus
MBS140339-05mg
MyBiosource
0.5mg
EUR 440
Mouse Anti Respiratory Enteric Orphan Virus
MBS140339-1mg
MyBiosource
1mg
EUR 600
Mouse Anti Respiratory Enteric Orphan Virus
MBS140339-5x1mg
MyBiosource
5x1mg
EUR 2375
Anti- Orphan nuclear receptor EAR-2 Antibody
GWB-8AE8C4
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor EAR-2 Antibody
GWB-B9F321
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor EAR-2 Antibody
GWB-D37B4B
GenWay Biotech
0.05 ml
Ask for price
Anti- Orphan nuclear receptor EAR-2 Antibody
GWB-835BD4
GenWay Biotech
0.05 ml
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx027769-400l
Abbexa
400 µl
EUR 518.75
RAR Related Orphan Receptor Beta (RORB) Antibody
abx027769-400ul
Abbexa
400 ul
EUR 627.6
RAR Related Orphan Receptor Beta (RORB) Antibody
abx027769-80l
Abbexa
80 µl
EUR 250
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214131-100l
Abbexa
100 µl
EUR 350
RAR Related Orphan Receptor Beta (RORB) Antibody
20-abx214131
Abbexa
Ask for price
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214131-200l
Abbexa
200 µl
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214131-40l
Abbexa
40 µl
EUR 250
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214132-100l
Abbexa
100 µl
EUR 350
RAR Related Orphan Receptor Beta (RORB) Antibody
20-abx214132
Abbexa
Ask for price
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214132-200l
Abbexa
200 µl
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx214132-40l
Abbexa
40 µl
EUR 250
Rar-Related Orphan Receptor A (RORA) Antibody
abx115045-100l
Abbexa
100 µl
EUR 612.5
Rar-Related Orphan Receptor A (RORA) Antibody
20-abx115045
Abbexa
Ask for price
Ask for price
Rar-Related Orphan Receptor B (RORB) Antibody
abx115046-100l
Abbexa
100 µl
EUR 612.5
Rar-Related Orphan Receptor B (RORB) Antibody
20-abx115046
Abbexa
Ask for price
Ask for price
Rar-Related Orphan Receptor C (RORC) Antibody
abx115047-100l
Abbexa
100 µl
EUR 612.5
Rar-Related Orphan Receptor C (RORC) Antibody
20-abx115047
Abbexa
Ask for price
Ask for price
RAR Related Orphan Receptor Beta (RORB) Antibody
abx237388-100g
Abbexa
100 µg
EUR 350
RAR Related Orphan Receptor Beta (RORB) Antibody
abx237388-100ug
Abbexa
100 ug
EUR 610.8
RAR Related Orphan Receptor Gamma (RORG) Protein
20-abx261968
Abbexa
Ask for price
Ask for price
Ask for price
Anti- RAR-related orphan receptor B Antibody
GWB-DA40DA
GenWay Biotech
0.05 ml
Ask for price
Anti- RAR-related orphan receptor B Antibody
GWB-B1C150
GenWay Biotech
0.05 ml
Ask for price
Anti- RAR-related orphan receptor B Antibody
GWB-B781E5
GenWay Biotech
0.05 ml
Ask for price
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx025951-400l
Abbexa
400 µl
EUR 518.75
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx025951-400ul
Abbexa
400 ul
EUR 627.6
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx025951-80l
Abbexa
80 µl
EUR 281.25
RAR Related Orphan Receptor Gamma (RORG) Antibody
abx013514-100g
Abbexa
100 µg
EUR 237.5
RAR Related Orphan Receptor Gamma (RORG) Antibody
20-abx013514
Abbexa
Ask for price
Ask for price
Ask for price
Ask for price
10 ug
100 ug
200 ug
300 µg
RAR Related Orphan Receptor Gamma (RORG) Antibody
abx013514-10g
Abbexa
10 µg
EUR 43.75
RAR Related Orphan Receptor Gamma (RORG) Antibody
abx013514-200g
Abbexa
200 µg
EUR 312.5
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx005288-100l
Abbexa
100 µl
EUR 400
RAR Related Orphan Receptor Alpha (RORA) Antibody
20-abx005288
Abbexa
Ask for price
Ask for price
Ask for price
Ask for price
20 ul
50 ul
100 ul
200 ul
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx005288-20l
Abbexa
20 µl
EUR 175
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx005288-50l
Abbexa
50 µl
EUR 275
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
abx130085-100l
Abbexa
100 µl
EUR 287.5
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
20-abx130085
Abbexa
Ask for price
Ask for price
Ask for price
Ask for price
Ask for price
10 ug
50 ug
100 ug
200 ug
1 mg
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
abx130085-1ml
Abbexa
1 ml
EUR 812.5
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
abx130085-200l
Abbexa
200 µl
EUR 362.5
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
20-abx173779
Abbexa
Ask for price
Ask for price
Neuron Derived Orphan Receptor 1 (NOR1) Antibody
abx173779-1ml
Abbexa
1 ml
EUR 850
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx338779-100g
Abbexa
100 µg
EUR 362.5
RAR Related Orphan Receptor Alpha (RORA) Antibody
20-abx338779
Abbexa
Ask for price
Ask for price
Ask for price
Ask for price
Ask for price
20 ug
50 ug
100 ug
200 ug
1 mg
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx338779-20g
Abbexa
20 µg
EUR 162.5
RAR Related Orphan Receptor Alpha (RORA) Antibody
abx338779-50g
Abbexa
50 µg
EUR 250
RAR Related Orphan Receptor Gamma (RORg) Antibody
20-abx178212
Abbexa
Ask for price
Ask for price
RAR Related Orphan Receptor Gamma (RORg) Antibody
abx178212-96tests
Abbexa
96 tests
EUR 287.5
RAR Related Orphan Receptor Gamma (RORG) Antibody
abx217274-100tests
Abbexa
100 tests
Ask for price
RAR Related Orphan Receptor Gamma (RORG) Antibody
abx217274-200tests
Abbexa
200 tests
Ask for price